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Received August 29, 2003; de novo received October 9, 2003; revision received November 10, 2003; accepted November 25, 2003. From the Department of Anesthesiology W.C.L., C.J.N., A.S.H., A.R.T. ; , University of Michigan, Ann Arbor, Mich; Sinai Center for Thrombosis Research P.A.G. ; , Sinai Hospital of Baltimore, Baltimore, Md; General Clinical Research Center P.B.W. ; , University of North Carolina, Chapel Hill, NC; Division of Thrombosis D.G.M.C., K.E.G. ; , Department of Chemistry, Indiana University, South Bend, Indiana; and Division of Cardiovascular Diseases E.R.B. ; , Department of Internal Medicine, University of Michigan, Ann Arbor, Mich. This article originally appeared Online on January 5, 2004 Circulation. 2004; 109: r1r6 ; . Correspondence to Wei C. Lau, MD, Department of Anesthesiology, University of Michigan Health System, 1G323 University Hospital, Box 0048, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0048. E-mail weiclau umich 2004 American Heart Association, Inc. Circulation is available at : circulationaha DOI: 10.1161 01.CIR.0000112378.09325.F9.
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Preventive therapy should be used in patients who have Recurrent migraines that persist and significantly interfere with patient's daily routine despite treatment Frequent headaches Contraindication to, failure of, or overuse of acute therapies AEs with acute therapies Patient preference for preventive therapy Key management concepts Initiate therapy with lowest effective dose and increase slowly until clinical benefit is achieved without AEs Give each treatment an adequate trial; medications may take 2 to 3 months to demonstrate effectiveness Avoid interfering medications--acute medications may impede effectiveness of preventive medications. Monitor and limit use of acute medications Use of long-acting formulations may improve compliance Patient education is critical to maximize compliance Encourage patients to keep headache diaries After a period of stability, re-evaluate therapy and consider tapering or discontinuing treatment Behavioral therapy goals Reduce frequency and severity of headaches Reduce headache-related disability Reduce reliance on poorly tolerated or unwanted pharmacotherapies Enhance personal control of migraines Reduce headache-related distress and psychological symptoms When to refer Patient's symptoms remain unchanged despite treatment efforts, initial diagnosis is in question, or physician or patient discomfort with progress of therapy exists Patient's level of disability worsens despite treatment Status of symptomatology changes, no longer fitting diagnostic criteria Comorbid conditions exist requiring special care or complex polypharmacy Patient is or becomes habituated, has failed attempts at detoxification, or rebound headaches limit outpatient management.
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TOTAL RECEIVING CASH ASSISTANCE, TOTAL Aged Blind Disabled AFDC-Child AFDC-Adult AFDC-Unemployed-Child AFDC-Unemployed-Adult MEDICALLY NEEDY, TOTAL Aged Blind Disabled AFDC-Child AFDC-Adult POVERTY RELATED, TOTAL Aged Blind Disabled AFDC-Child AFDC-Adult OTHER Source: CMS, HCFA-64 Report, FY 1999 and FY 2000. * Data on recipients and expenditures by maintenance assistance status and basis of eligibility are unavailable. 1999 * Recipients Expended 0, 829, 923 2000 * Expended 4, 782, 642 Recipients and venlafaxine.
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